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KMID : 1040020190100010010
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International Journal of Pain
2019 Volume.10 No. 1 p.10 ~ p.16
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The Effect of Atelocollagen on the Treatment of Chronic Anterior Talofibular Ligament Tear: A Case Report
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Jin So-Hee
Kim Won-Joong
Park Hahck-Soo
Kim Chi-Hyo
Chung Rack-Kyung
Baik Hee-Jung
Han Jong-In
Kim Dong-Yeon
Lee Hee-Seung
Cho Soo-Young
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Abstract
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Lateral ankle instability is most common ankle injury. The anterior talofibular ligament (ATFL) is a key ligament in the lateral ankle and the most common injury site in lateral ligaments. Treatment options are variable. Atelocollagen is type I collagen found in skin, tendon, vasculature, organs, and bone. Atelocollagen is a collagen that removes C-terminal and N-terminal, which are antigen binding sites. It does not cause an inflammatory response in the body, so more biocompatible. Here, we report a case of a 24-year-old man with chronic ATFL tear treated with atelocollagen under ultrasonography. He rated pain as 7 of 10 on a numeric rating scale (NRS). We first considered prolotherapy with polydeoxyribonucleotide, and repeatedly 4 times in 2 months. But he complained of constant discomfort, we planned the atelocollagen injection. At the 4 weeks follow up after the first injection, the pain was reduced by half. The atelocollagen was repeatedly administrated one more. The patient reported signi?cant pain reduction with NRS from 7 to 2.
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KEYWORD
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ankle Injury, ankle sprain, ankle lateral ligament, collagen, type I collagen
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